Structure of PDB 5xv0 Chain F

Receptor sequence
>5xv0F (length=239) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence]
RGSHHHHHHGSMDRPFIFINSAMSADGKLSTKERKQVKISGKLNFERMDE
LRAHADAIMVGIGTVLADDPSLTVKSPERKAARKAAGKSENPVRVVVDSS
ARTPLNADIFKKGEGLRIIAVSNSAPEEKIRMLEEKALVIKTGAFRVDLT
ELAAKLKEMGINSLMVEGGATLNWGMLSAGLVDEVYTFVGNLIIGGKTAP
TFTDGEGFTENELLGLELSSAEKIEDGILLKWKVKGKKN
3D structure
PDB5xv0 Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis: Substrate specificity and cofactor preference.
ChainF
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.302: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP F A11 L18 S19 R23 G50 I51 G52 T53 D57 V86 S88 V136 L138 G158 A159 T160 L161 A22 L29 S30 R34 G61 I62 G63 T64 D68 V97 S99 V147 L149 G169 A170 T171 L172
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0009231 riboflavin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5xv0, PDBe:5xv0, PDBj:5xv0
PDBsum5xv0
PubMed29864427
UniProtQ8PYN5

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