Structure of PDB 5x6m Chain F

Receptor sequence
>5x6mF (length=121) Species: 10090 (Mus musculus) [Search protein sequence]
PAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQP
SKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEF
PFGSKQKEVCINPYHYKRVES
3D structure
PDB5x6m Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
ChainF
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F S71 L72 L76 Q77 S79 K82 S59 L60 L64 Q65 S67 K70
BS02 dna F R75 K82 H102 R63 K70 H90
BS03 ZN F C65 C122 H127 C53 C110 H115
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005667 transcription regulator complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5x6m, PDBe:5x6m, PDBj:5x6m
PDBsum5x6m
PubMed26304548
UniProtP97454|SMAD5_MOUSE Mothers against decapentaplegic homolog 5 (Gene Name=Smad5)

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