Structure of PDB 5wqd Chain F

Receptor sequence
>5wqdF (length=195) Species: 9606 (Homo sapiens) [Search protein sequence]
AGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLG
KEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTE
FTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKTTQKLRNDLLNII
REKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKAL
3D structure
PDB5wqd NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres
ChainF
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F R80 Q84 L87 S98 R102 Q105 R109 C118 S119 F120 R38 Q42 L45 S56 R60 Q63 R67 C76 S77 F78
Gene Ontology
Molecular Function
GO:0042162 telomeric DNA binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0000723 telomere maintenance
GO:0031848 protection from non-homologous end joining at telomere
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5wqd, PDBe:5wqd, PDBj:5wqd
PDBsum5wqd
PubMed28216226
UniProtQ15554|TERF2_HUMAN Telomeric repeat-binding factor 2 (Gene Name=TERF2)

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