Structure of PDB 5nkk Chain F

Receptor sequence
>5nkkF (length=253) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
MKESVRFLTDFGEISDAISDLLTSSPNFNVISAIGPQGAGKSTLLSMLAG
NNSRQMYREYVFRPVSTIQIDIYIVNHQIFLDCDDSTAMSDTLRLTAFLL
YVSHTVLVVSETHYDKVIIDTLRVAEQIRPYLAIFRPKLAIDRKTNLVFI
KTKASSIDLAPTVIREREELLRLSFQDSRWLKVSQEPFKTLIVLEEFDEQ
IAELREELQKNREDFTVETAAMDEKKWLDMCREVIRDKTLHKTLKEYQRA
MTD
3D structure
PDB5nkk Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
ChainF
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP F Q95 G98 K99 S100 T101 P122 K241 E284 Q37 G40 K41 S42 T43 P64 K153 E196 PDBbind-CN: -logKd/Ki=5.00,Kd=10uM
Gene Ontology
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

View graph for
Biological Process
External links
PDB RCSB:5nkk, PDBe:5nkk, PDBj:5nkk
PDBsum5nkk
PubMed28389433
UniProtQ9XWJ1|SMG9_CAEEL Nonsense-mediated mRNA decay factor SMG9 (Gene Name=smg-9)

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