Structure of PDB 5ldx Chain F

Receptor sequence
>5ldxF (length=425) Species: 9913 (Bos taurus) [Search protein sequence]
SLKDEDRIFTNLYGRHDWRLKGAQSRGDWYKTKEILLKGPDWILGEVKTS
GLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREIIRH
DPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAGLIG
KNACGSGYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADV
GVFGCPTTVANVETVAVSPTICRRGGAWFASFGRERNSGTKLFNISGHVN
NPCTVEEEMSVPLKELIEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCE
TVLMDFDALIQAQTGLGTAAVIVMDRSTDIVKAIARLIEFYKHESCGQCT
PCREGVDWMNKVMARFVRGDARPAEIDSLWEISKQIEGHTICALGDGAAW
PVQGLIRHFRPELEERMQQFAQQHQ
3D structure
PDB5ldx Structure of mammalian respiratory complex I.
ChainF
Resolution5.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN F G69 G70 A71 N96 G100 C186 G187 E189 A223 N224 A406 G56 G57 A58 N83 G87 C173 G174 E176 A210 N211 A393
BS02 SF4 F P203 C359 Q361 C362 C365 T403 C405 P190 C346 Q348 C349 C352 T390 C392
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051287 NAD binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ldx, PDBe:5ldx, PDBj:5ldx
PDBsum5ldx
PubMed27509854
UniProtP25708|NDUV1_BOVIN NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (Gene Name=NDUFV1)

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