Structure of PDB 5lc1 Chain F

Receptor sequence
>5lc1F (length=319) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
HMPRVLVTGALGQIGTDLSLALRDKFGADSVLVSDVVEPGAKHPLAGLKG
VEKLDCLDSNGFEKLVKEFKPTWMYHLPAIMSVRGEAEPDLAMDINVNTT
RYALELARKYNIRIFIPSTIAAFGDKCGKTMTKDDTIMNPSTVYGVTKVY
TELLGTWYRQKYGVDFRSVRLPGIISAATLPGGGATDYAIHMYHSALLQK
KCVCPVLPYESLPMMYMPDTLNSLVKIMEAPLEKLTRTVYNITGFSFSPS
ELRFSIERCTDRTIEVEYVEGPAQKIANSWPDSLDDSNARNDWGHQVKYD
IDMMSEDMLRQIPILHGLP
3D structure
PDB5lc1 Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
ChainF
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.103: L-threonine 3-dehydrogenase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD F G9 G12 Q13 I14 D35 V36 D55 C56 L77 P78 A79 M81 P117 T119 Y144 K148 L171 I174 G9 G12 Q13 I14 D35 V36 D55 C56 L77 P78 A79 M81 P117 T119 Y144 K148 L171 I174
BS02 PYR F M81 S82 T119 Y144 G184 W280 M81 S82 T119 Y144 G184 W280
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