Structure of PDB 5kww Chain F

Receptor sequence
>5kwwF (length=428) Species: 11259,11676 [Search protein sequence]
NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKAKVKLIKQELD
KYKNAVTELQLLMQFLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALL
STNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLPISISNIETVIEFQQKNN
RLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNV
QIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKE
GSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSE
VNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKN
RGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFY
DPLVFPSDEFDASISQVNEKINQSLAFI
3D structure
PDB5kww Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor.
ChainF
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6YA F F140 F488 D489 F68 F410 D411 MOAD: Kd=7.4nM
PDBbind-CN: -logKd/Ki=8.13,Kd=7.4nM
Gene Ontology
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane

View graph for
Biological Process
External links
PDB RCSB:5kww, PDBe:5kww, PDBj:5kww
PDBsum5kww
PubMed28761099
UniProtM1E1E4;
P03420|FUS_HRSVA Fusion glycoprotein F0 (Gene Name=F)

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