Structure of PDB 5j0n Chain F

Receptor sequence

>5j0nF (length=356) Species: 10710 (Lambdavirus lambda) [Search protein sequence]

MGRRRSHERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQ
ANIELFSGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINY
MSKIKAIRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDA
FREAIAEGHITTNHVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLR
LAMELAVVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTALHIDA
LGISMKETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSF
EGDPPTFHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREW
DKIEIK

3D structure

PDB

5j0n Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction.

Chain

Resolution

11.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.7.-
3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	F	M1 G2 R19 N21 Y23 K93 K95 T96 N99 Y100 D149 R152 K172 R177 S234 K235 S286 H308	M1 G2 R19 N21 Y23 K93 K95 T96 N99 Y100 D149 R152 K172 R177 S234 K235 S286 H308
BS02	dna	F	M1 G2 R3 S6 R9 Y17 N20 K136 L142 K235 T236 Y288 H333 M338	M1 G2 R3 S6 R9 Y17 N20 K136 L142 K235 T236 Y288 H333 M338

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0008907	integrase activity
GO:0016740	transferase activity
GO:0016787	hydrolase activity

	Biological Process
GO:0006310	DNA recombination
GO:0015074	DNA integration
GO:0032359	provirus excision
GO:0044826	viral genome integration into host DNA
GO:0046718	symbiont entry into host cell
GO:0075713	establishment of integrated proviral latency

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Molecular Function

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Biological Process

External links

PDB	RCSB:5j0n, PDBe:5j0n, PDBj:5j0n
PDBsum	5j0n
PubMed	27223329
UniProt	P03700\|VINT_LAMBD Integrase (Gene Name=int)

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