Structure of PDB 5ij7 Chain F

Receptor sequence
>5ij7F (length=360) Species: 9606 (Homo sapiens) [Search protein sequence]
SFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQG
EIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFG
GVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDY
NPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVC
WKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALG
NQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCD
DASIWRWDRL
3D structure
PDB5ij7 Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance.
ChainF
Resolution2.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6BN F R222 D223 R156 D157
External links
PDB RCSB:5ij7, PDBe:5ij7, PDBj:5ij7
PDBsum5ij7
PubMed27122193
UniProtO75530|EED_HUMAN Polycomb protein EED (Gene Name=EED)

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