Structure of PDB 5ffo Chain F

Receptor sequence
>5ffoF (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVE
KPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKN
QKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMD
SKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFA
VTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEEL
3D structure
PDB5ffo Force interacts with macromolecular structure in activation of TGF-beta.
ChainF
Resolution3.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN F S127 D130 D131 D254 S15 D18 D19 D142
BS02 MN F S125 S127 E223 S13 S15 E111
BS03 MN F E162 N218 D220 P222 E223 E50 N106 D108 P110 E111
External links
PDB RCSB:5ffo, PDBe:5ffo, PDBj:5ffo
PDBsum5ffo
PubMed28117447
UniProtP18564|ITB6_HUMAN Integrin beta-6 (Gene Name=ITGB6)

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