Structure of PDB 5eya Chain F

Receptor sequence
>5eyaF (length=76) Species: 9606 (Homo sapiens) [Search protein sequence]
PLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRA
VYQARPQLHKNTVLCNVVEQFLQADL
3D structure
PDB5eya Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.
ChainF
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
6.3.2.n3: ISG15--protein ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN F C28 H30 C50 C53 C23 H25 C45 C48
BS02 ZN F C13 C16 C33 C36 C8 C11 C28 C31
External links
PDB RCSB:5eya, PDBe:5eya, PDBj:5eya
PDBsum5eya
PubMed27425606
UniProtQ14258|TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 (Gene Name=TRIM25)

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