Structure of PDB 5ea5 Chain F

Receptor sequence
>5ea5F (length=426) Species: 11259 (Human respiratory syncytial virus A2) [Search protein sequence]
NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIDAKVKLIKQELD
KYKNAVTELQLLMQSTPATNFLGFLLGVGSAIASGVAVCKVLHLEGEVNK
IKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLTVIEFQQKNNRL
LEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQI
VRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGS
NICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVN
LCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRG
IIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDP
LVFPSDEFDASISQVNEKINQSLAFI
3D structure
PDB5ea5 Molecular mechanism of respiratory syncytial virus fusion inhibitors.
ChainF
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TM3 F F140 D486 E487 F488 F74 D406 E407 F408 PDBbind-CN: -logKd/Ki=8.06,Kd=8.7nM
Gene Ontology
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane

View graph for
Biological Process
External links
PDB RCSB:5ea5, PDBe:5ea5, PDBj:5ea5
PDBsum5ea5
PubMed26641933
UniProtP03420|FUS_HRSVA Fusion glycoprotein F0 (Gene Name=F)

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