Structure of PDB 5ea3 Chain F

Receptor sequence
>5ea3F (length=419) Species: 11259 (Human respiratory syncytial virus A2) [Search protein sequence]
NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKKVKLIKQELDK
YKNAVTELQLLMFLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLST
NKAVVSLSNGVSVLTFKVLDLKNYIDKQLLETVIEFQQKNNRLLEITREF
SVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYS
IMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRT
DRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIF
NPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSN
GCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDE
FDASISQVNEKINQSLAFI
3D structure
PDB5ea3 Molecular mechanism of respiratory syncytial virus fusion inhibitors.
ChainF
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5NK F F140 D486 F488 F66 D399 F401 PDBbind-CN: -logKd/Ki=8.77,Kd=1.7nM
Gene Ontology
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane

View graph for
Biological Process
External links
PDB RCSB:5ea3, PDBe:5ea3, PDBj:5ea3
PDBsum5ea3
PubMed26641933
UniProtP03420|FUS_HRSVA Fusion glycoprotein F0 (Gene Name=F)

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