Structure of PDB 5cjp Chain F

Receptor sequence
>5cjpF (length=372) Species: 9606 (Homo sapiens) [Search protein sequence]
SKERRKTLETYQQLFYLLQTNPLYLAKLIFQMPQNKSTKFMDTVIFTLYN
YASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRG
ARGQNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVNQLETQTGEASK
LPYDVTTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLR
YIAKVLKNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDM
TAGGQINSDQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQE
FRKYFKEACNVPEPEEKFNMDKYTDLVTVSKPVIYISIEEIISTHSLLLE
HQDAIAPEKNDLLSELLGSLGE
3D structure
PDB5cjp The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.
ChainF
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP F N928 R930 E931 Y1197 N54 R56 E57 Y323
Gene Ontology
Biological Process
GO:0043087 regulation of GTPase activity

View graph for
Biological Process
External links
PDB RCSB:5cjp, PDBe:5cjp, PDBj:5cjp
PDBsum5cjp
PubMed27524202
UniProtQ13576|IQGA2_HUMAN Ras GTPase-activating-like protein IQGAP2 (Gene Name=IQGAP2)

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