Structure of PDB 5c8e Chain F

Receptor sequence
>5c8eF (length=270) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
VYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRHRLYSAEDVEALKTIKRW
LEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRF
WGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLA
GFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRA
LARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRL
GAEYMEDLKGLAEALWLPRG
3D structure
PDB5c8e Structural basis for gene regulation by a B12-dependent photoreceptor.
ChainF
Resolution3.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F Q25 R29 Y30 P66 K67 Q20 R24 Y25 P57 K58
BS02 B12 F L121 L124 G128 E141 G174 R176 H177 E178 G180 S222 L225 G247 G248 Q249 M264 L267 L112 L115 G119 E132 G165 R167 H168 E169 G171 S213 L216 G238 G239 Q240 M255 L258
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0031419 cobalamin binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:5c8e, PDBe:5c8e, PDBj:5c8e
PDBsum5c8e
PubMed26416754
UniProtQ746J7

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