Structure of PDB 5b4w Chain F

Receptor sequence
>5b4wF (length=438) Species: 9606 (Homo sapiens) [Search protein sequence]
TAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLD
SRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLG
QLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSR
GGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASA
YFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQA
AAVATSREVAHGEVLFAAFSSASGASALCAFPLDEVDRLANRTRDACYTR
EGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLE
ATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYS
TQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVAS
3D structure
PDB5b4w Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide
ChainF
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F S241 R245 G270 R272 T351 E352 P391 S213 R217 G242 R244 T308 E309 P348
BS02 peptide F Q240 S241 P325 T395 I397 E399 D414 G415 H416 T417 L433 G434 S437 Q212 S213 P282 T352 I354 E356 D371 G372 H373 T374 L390 G391 S394
Gene Ontology
Molecular Function
GO:0017154 semaphorin receptor activity
Biological Process
GO:0071526 semaphorin-plexin signaling pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:5b4w, PDBe:5b4w, PDBj:5b4w
PDBsum5b4w
PubMed27984026
UniProtO43157|PLXB1_HUMAN Plexin-B1 (Gene Name=PLXNB1)

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