Structure of PDB 4xlq Chain F

Receptor sequence

>4xlqF (length=345) Species: 271 (Thermus aquaticus) [Search protein sequence]

DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIR
EVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAR
EGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFE
YKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQL
QQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSF
YGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDG
REHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE

3D structure

PDB

4xlq Structure of a bacterial RNA polymerase holoenzyme open promoter complex.

Chain

Resolution

4.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	F	N206 R208 L209 R237 K241 F242 E243 R246 F248 K249 S251 T252 Y253 T255 W256 W257 Q260 R264 R274 P276 V277 H278 V407 E410 R411 Q414	N113 R115 L116 R144 K148 F149 E150 R153 F155 K156 S158 T159 Y160 T162 W163 W164 Q167 R171 R181 P183 V184 H185 V314 E317 R318 Q321
BS02	dna	F	R220 N263 E281 N284 R387 T397 L398 R409 E410 R413	R127 N170 E188 N191 R294 T304 L305 R316 E317 R320

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity
GO:0016987	sigma factor activity

	Biological Process
GO:0006352	DNA-templated transcription initiation
GO:0006355	regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:4xlq, PDBe:4xlq, PDBj:4xlq
PDBsum	4xlq
PubMed	26349032
UniProt	Q9EZJ8\|SIGA_THEAQ RNA polymerase sigma factor SigA (Gene Name=sigA)

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