Structure of PDB 4wk8 Chain F

Receptor sequence
>4wk8F (length=80) Species: 9606 (Homo sapiens) [Search protein sequence]
RPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIR
HNLSLHKCFVRVESEKGAVWTVDELEFRKK
3D structure
PDB4wk8 DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.
ChainF
Resolution3.4006 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F R386 H387 S390 R397 W406 R50 H51 S54 R61 W70
BS02 dna F P378 N383 H387 P42 N47 H51
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4wk8, PDBe:4wk8, PDBj:4wk8
PDBsum4wk8
PubMed25567984
UniProtQ9BZS1|FOXP3_HUMAN Forkhead box protein P3 (Gene Name=FOXP3)

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