Structure of PDB 4s0h Chain F

Receptor sequence
>4s0hF (length=53) Species: 9606 (Homo sapiens) [Search protein sequence]
RVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRY
KSK
3D structure
PDB4s0h Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5.
ChainF
Resolution2.817 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F Q144 W148 N151 Q40 W44 N47
BS02 dna F Y125 Q150 R153 Y154 K157 Y21 Q46 R49 Y50 K53
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:4s0h, PDBe:4s0h, PDBj:4s0h
PDBsum4s0h
PubMed26926761
UniProtP52952|NKX25_HUMAN Homeobox protein Nkx-2.5 (Gene Name=NKX2-5)

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