Structure of PDB 4s0h Chain F
Receptor sequence
>4s0hF (length=53) Species:
9606
(Homo sapiens) [
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RVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRY
KSK
3D structure
PDB
4s0h
Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5.
Chain
F
Resolution
2.817 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
dna
F
Q144 W148 N151
Q40 W44 N47
BS02
dna
F
Y125 Q150 R153 Y154 K157
Y21 Q46 R49 Y50 K53
Gene Ontology
Molecular Function
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677
DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:4s0h
,
PDBe:4s0h
,
PDBj:4s0h
PDBsum
4s0h
PubMed
26926761
UniProt
P52952
|NKX25_HUMAN Homeobox protein Nkx-2.5 (Gene Name=NKX2-5)
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