Structure of PDB 4pw5 Chain F

Receptor sequence
>4pw5F (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
VPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVL
AGGFADEVDRGDEFTYTGSGSADQTLTNMNRALALNCDAPLDDKIGAESR
NWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFL
VWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGY
3D structure
PDB4pw5 Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
ChainF
Resolution2.204 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F F461 R462 V475 G476 G477 A492 G494 Y507 T508 K569 F20 R21 V34 G35 G36 A51 G53 Y66 T67 K115
External links
PDB RCSB:4pw5, PDBe:4pw5, PDBj:4pw5
PDBsum4pw5
PubMed24813944
UniProtQ96PU4|UHRF2_HUMAN E3 ubiquitin-protein ligase UHRF2 (Gene Name=UHRF2)

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