Structure of PDB 4p9u Chain F

Receptor sequence
>4p9uF (length=272) Species: 666 (Vibrio cholerae) [Search protein sequence]
KSPAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRL
ARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAAR
TNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAE
KIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIF
NGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQY
GIASGHIWNQMKMTLPSNFTED
3D structure
PDB4p9u The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand.
ChainF
Resolution3.208 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F A33 E34 R35 R45 R49 I63 H65 G66 T69 A28 E29 R30 R40 R44 I58 H60 G61 T64
BS02 dna F P8 A9 T44 T46 T47 H65 G66 K67 P3 A4 T39 T41 T42 H60 G61 K62
Gene Ontology
Molecular Function
GO:0000062 fatty-acyl-CoA binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006631 fatty acid metabolic process
GO:0019217 regulation of fatty acid metabolic process
GO:0071072 negative regulation of phospholipid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Cellular Component
External links
PDB RCSB:4p9u, PDBe:4p9u, PDBj:4p9u
PDBsum4p9u
PubMed25607896
UniProtQ9KQU8|FADR_VIBCH Fatty acid metabolism regulator protein (Gene Name=fadR)

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