Structure of PDB 4ol8 Chain F

Receptor sequence
>4ol8F (length=427) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KDTFCTLPVWLQQKYREIIRNDLPPRPAPVKHDIEIKPGARLPRLQPYHV
TEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPKKDGTFRLCVDYRT
LNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKT
AFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFS
ESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAP
LQHKCAAIRDFPTKQAQRFLGMINYYRRFIPNCSKIAQPTEKQDKAIDKL
KDALCNSPVLVPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVGVVGYF
SKSYPAGELELLGIIKALHHFRYMLHGKHFTLRTNHISLLSLQNKNEPAR
RVQRWLDDLATYDFTLEYLVVADAISR
3D structure
PDB4ol8 Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry.
ChainF
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F Q434 N435 K436 Q393 N394 K395
External links
PDB RCSB:4ol8, PDBe:4ol8, PDBj:4ol8
PDBsum4ol8
PubMed24608367
UniProtQ99315|YG31B_YEAST Transposon Ty3-G Gag-Pol polyprotein (Gene Name=TY3B-G)

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