Structure of PDB 4l18 Chain F

Receptor sequence
>4l18F (length=106) Species: 9606 (Homo sapiens) [Search protein sequence]
SGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNK
PKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHA
MLDVKP
3D structure
PDB4l18 Structural basis of Ets1 activation by Runx1.
ChainF
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F Q336 L337 W375 K379 K381 M384 K388 R391 Y396 Q5 L6 W44 K48 K50 M53 K57 R60 Y65
BS02 dna F K381 Y386 R391 R394 Y397 K404 Y410 K50 Y55 R60 R63 Y66 K73 Y79
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:4l18, PDBe:4l18, PDBj:4l18
PDBsum4l18
PubMed24646888
UniProtP14921|ETS1_HUMAN Protein C-ets-1 (Gene Name=ETS1)

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