Structure of PDB 4kyi Chain F

Receptor sequence
>4kyiF (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDT
TVKFEIWDTAGLERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKE
LQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTA
MNVNEIFMAIAKKL
3D structure
PDB4kyi Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5.
ChainF
Resolution3.075 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP F S30 G33 K34 S35 S36 E48 S52 T53 N134 K135 D137 S164 A165 S12 G15 K16 S17 S18 E30 S34 T35 N116 K117 D119 S146 A147
BS02 MG F S35 T53 S17 T35
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4kyi, PDBe:4kyi, PDBj:4kyi
PDBsum4kyi
PubMed25114243
UniProtP51148|RAB5C_HUMAN Ras-related protein Rab-5C (Gene Name=RAB5C)

[Back to BioLiP]