Structure of PDB 4k6t Chain F

Receptor sequence
>4k6tF (length=186) Species: 52275 (Human adenovirus D37) [Search protein sequence]
KYDTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGK
YHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTA
YEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQ
ETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
3D structure
PDB4k6t Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
ChainF
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA F Y308 V322 Y129 V143
BS02 ZN F H231 E351 H52 E172
BS03 SIA F Y312 P317 K345 Y133 P138 K166
BS04 MG F D201 K202 D22 K23
BS05 MG F K212 E365 K33 E186
Gene Ontology
Biological Process
GO:0007155 cell adhesion
GO:0019058 viral life cycle
GO:0019062 virion attachment to host cell
Cellular Component
GO:0019028 viral capsid

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4k6t, PDBe:4k6t, PDBj:4k6t
PDBsum4k6t
PubMed26177934
UniProtQ64823

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