Structure of PDB 4ilm Chain F

Receptor sequence

>4ilmF (length=278) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence]

MPLIFKIGYNVIPLQDVILPTPSSKVLKYLIQSGKLIPSLKDLITSRDKY
KPIFISHLGFNQRRIFQTNKTITKGSRLSSIIAFSTQANVLSEVADEGIF
ETVYGKFHIMIESIEIVEVEKLKEEVEKHMNDNIRVRFVSPTLLSSKVLL
PPSLSERYKKIHAGYSTLPSVGLIVAYAYNVYCNLIGKKEVEVRAFKFGI
LSNALSRIIGYDLHPVTVAIGEDSLRKARGVMGWIEFDIPDERLKRRALN
YLLTSSYLGIGRSRGIGFGEIRLEFRKI

3D structure

PDB

4ilm Recognition and cleavage of a nonstructured CRISPR RNA by its processing endoribonuclease Cas6.

Chain

Resolution

3.068 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	F	K28 R47 D48 K49 Y50 K51 S148 K150 V151 L153 K162 G167 Y168 Y180 T220 I223 L231 R232 K233 A234 R235 R268 S269 R270 I272	K28 R47 D48 K49 Y50 K51 S145 K147 V148 L150 K159 G164 Y165 Y177 T217 I220 L225 R226 K227 A228 R229 R262 S263 R264 I266
BS02	rna	F	N136 R210 I212 Y214 R282	N133 R207 I209 Y211 R276

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0004519	endonuclease activity
GO:0016788	hydrolase activity, acting on ester bonds

	Biological Process
GO:0051607	defense response to virus

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Molecular Function

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Biological Process

External links

PDB	RCSB:4ilm, PDBe:4ilm, PDBj:4ilm
PDBsum	4ilm
PubMed	23454186
UniProt	Q97WV8\|CAS6B_SACS2 CRISPR-associated endoribonuclease Cas6 2 (Gene Name=cas6b)

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