Structure of PDB 4hcy Chain F

Receptor sequence
>4hcyF (length=352) Species: 5762 (Naegleria gruberi) [Search protein sequence]
PKTLTVGLFPYLPSWNENGNEVKLINLIKDVLPTQVSGYNIEYTEFDCYS
DASLQSLPDVFSTDSIFLPYLVSLGGVKSLDESLVRGVTGDLHSFVSSSA
SVNGSVYGFPQYLCSNFLLSSPNATQQASSLLELAQKVGYEQIVYPDVAS
SSSFTVFGLYQQLLQSSSSAAVDIKASDLPQSGDQVNKDITQKYRTILDS
TVVASQREYINSVKQGKPISNYYVGYSESMCEIKDIIRDQQYNVQLIGTS
DKPYVYTDVLALNSNLCDEKQKVAVEVIKNLLTNTLVLDLLGLGLTLPAN
KNGIAHLAKSSNFYAQLSQQFDAKESEVRVLRCVDFANKEVKNCAGVLRP
FL
3D structure
PDB4hcy Structure of a eukaryotic thiaminase I.
ChainF
Resolution2.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C118 E232 D262
Catalytic site (residue number reindexed from 1) C114 E228 D258
Enzyme Commision number 2.2.1.1: transketolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0YN F F13 Y53 D68 C118 F158 Y230 E232 D262 F9 Y49 D64 C114 F154 Y226 E228 D258
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