Structure of PDB 4f9f Chain F

Receptor sequence
>4f9fF (length=460) Species: 264445 (Streptomyces hygroscopicus subsp. limoneus) [Search protein sequence]
SEIFLASKRAAITYDPRAWLAPGGTGNVVAEQAGVLNISWIASADSEDDR
RASALNPDGVTMELREILVRLIRHDPAVFRNVQNFMTANLMWAANNYGWD
RWTQPSFGSDAREGWADFGRFTRDFADAILKSSAQSADPVYLVHDYQLVG
VPALLREQRPDAPILLFVHIPWPSADYWRILPKEIRTGILHGMLPATTIG
FFADRWCRNFLESVADLLPDARIDREAMTVEWRGHRTRLRTMPLGYSPNP
QLPEGIEEWADGHRLVVHSGRTDPIKNAERAVRAFVLAARGGGLEKTRML
VRMNPNRLYVPANADYVHRVETAVAEANAELGSDTVRIDNDNDVNHTIAC
FRRADLLIFNSTVDGQNLSTFEAPLVNERDADVILSETCGAAEVLGEYCR
SVNPFDLVEQAEAISAALAAGPRQRAEAAARRRDAARPWTLEAWVQAQLD
GLAADHAART
3D structure
PDB4f9f Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex.
ChainF
Resolution2.807 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H182 D383
Catalytic site (residue number reindexed from 1) H169 D364
Enzyme Commision number 2.5.1.135: validamine 7-phosphate valienyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP F P32 G33 R290 K295 N323 N361 D362 V363 T366 L387 S388 E391 P22 G23 R271 K276 N304 N342 D343 V344 T347 L368 S369 E372
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0005992 trehalose biosynthetic process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4f9f, PDBe:4f9f, PDBj:4f9f
PDBsum4f9f
PubMed23028689
UniProtQ15JG1|VLDE_STRHL Validamine 7-phosphate valienyltransferase (Gene Name=vldE)

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