Structure of PDB 4csu Chain F

Receptor sequence

>4csuF (length=178) Species: 83333 (Escherichia coli K-12)

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFRK

3D structure

• PDB: 4csu Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
• Chain: F
• Resolution: 5.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	F	N22 S23 M25 Q26 K32 Q62 K63 P64 L65 T89 R91 W96	N22 S23 M25 Q26 K32 Q62 K63 P64 L65 T89 R91 W96
BS02	rna	F	T34 N36 G38 G40 E41 T67 R70 K71 S72 V73 A74 F76 I84 G85 S117 S120 F121 D122 G123 S128 G130 V131 R132 R147 V148 G150 L151 D152 T154	T34 N36 G38 G40 E41 T67 R70 K71 S72 V73 A74 F76 I84 G85 S117 S120 F121 D122 G123 S128 G130 V131 R132 R147 V148 G150 L151 D152 T154

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4csu, PDBe:4csu, PDBj:4csu
• PDBsum: 4csu
• PubMed: 24844575
• UniProt: P62399|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)