Structure of PDB 4chg Chain F

Receptor sequence
>4chgF (length=133) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
AMIVDTSVWIAYLSTSESLASRWLADRIAADSTVIVPEVVMMELLIGKTD
EDTAALRRRLLQRFAIEPLAPVRDAEDAAAIHRRCRRGGDTVRSLIDCQV
AAMALRIGVAVAHRDRDYEAIRTHCGLRTEPLF
3D structure
PDB4chg Crystal Structure of the Vapbc-15 Complex from Mycobacterium Tuberculosis Reveals a Two-Metal Ion Dependent Pin-Domain Ribonuclease And a Variable Mode of Toxin-Antitoxin Assembly.
ChainF
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN F D96 D114 D116 D97 D115 D117
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004518 nuclease activity
GO:0004540 RNA nuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0001666 response to hypoxia
GO:0045926 negative regulation of growth

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Molecular Function
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Biological Process
External links
PDB RCSB:4chg, PDBe:4chg, PDBj:4chg
PDBsum4chg
PubMed25450593
UniProtP9WF97|VPC15_MYCTU Ribonuclease VapC15 (Gene Name=vapC15)

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