Structure of PDB 4biu Chain F

Receptor sequence
>4biuF (length=250) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
KPARKLKNAADEVFLAAGASFNQMVTALERMMTSQQRLLSDISHELRTPL
TRLQLGTALLRRRSGESKELERIETEAQRLDSMINDLLVMSRNQQKNALV
SETIKANQLWSEVLDNAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESAL
ENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFY
RTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLY
3D structure
PDB4biu Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation.
ChainF
Resolution3.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP F N360 R363 Y364 D386 P389 V391 I399 R405 T406 A409 G420 L421 L445 N156 R159 Y160 D182 P185 V187 I195 R201 T202 A205 G216 L217 L241
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4biu, PDBe:4biu, PDBj:4biu
PDBsum4biu
PubMed24492262
UniProtP0AE82|CPXA_ECOLI Sensor histidine kinase CpxA (Gene Name=cpxA)

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