Structure of PDB 3t80 Chain F

Receptor sequence
>3t80F (length=146) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
AMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALL
GAAALGDIGKLDSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIP
QMRVFIAEDLGCHMDEVNVKATTTEKLGFTGRGEGIACEAVALLMK
3D structure
PDB3t80 Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine
ChainF
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.12: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 POP F G138 F139 R142 G128 F129 R132
BS02 ZN F D8 H10 D9 H11
BS03 CTN F A100 K104 M105 L106 A131 T132 A90 K94 M95 L96 A121 T122
Gene Ontology
Molecular Function
GO:0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0016114 terpenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway

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Molecular Function

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Biological Process
External links
PDB RCSB:3t80, PDBe:3t80, PDBj:3t80
PDBsum3t80
PubMed
UniProtQ8ZMF7|ISPF_SALTY 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Gene Name=ispF)

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