Structure of PDB 3otw Chain F

Receptor sequence
>3otwF (length=156) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence]
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDE
RLKMIQLATKSFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYEL
QMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEI
YPLISK
3D structure
PDB3otw Structural and Functional Studies of Helicobacter pylori Wild-Type and Mutated Proteins Phosphopantetheine adenylyltransferase
ChainF
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H18 K42 R91 S129
Catalytic site (residue number reindexed from 1) H18 K42 R91 S129
Enzyme Commision number 2.7.7.3: pantetheine-phosphate adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA F S134 H138 S134 H138
BS02 COA F P8 G9 T10 T15 G17 H18 K42 F70 L73 L74 R88 R91 Y98 N106 I127 S128 R133 P8 G9 T10 T15 G17 H18 K42 F70 L73 L74 R88 R91 Y98 N106 I127 S128 R133
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004595 pantetheine-phosphate adenylyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0015937 coenzyme A biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3otw, PDBe:3otw, PDBj:3otw
PDBsum3otw
PubMed
UniProtO26010|COAD_HELPY Phosphopantetheine adenylyltransferase (Gene Name=coaD)

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