Structure of PDB 3occ Chain F

Receptor sequence
>3occF (length=238) Species: 502800 (Yersinia pseudotuberculosis YPIII) [Search protein sequence]
ATPHINAEMGDFADVVLMPGDPLRAKFIAETFLQDVREVNNVRGMLGFTG
TYKGRKISVMGHGMGIPSCSIYAKELITDFGVKKIIRVGSCGAVRTDVKL
RDVVIGMGACTDSKVNRMRFKDHDYAAIADFEMTRNAVDAAKAKGVNVRV
GNLFSADLFYTPDPQMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTIC
TVSDHIRTGEQTTAAERQTTFNDMIEIALESVLLGDNA
3D structure
PDB3occ crystal structure of PNP with DADMEimmH from Yersinia pseudotuberculosis
ChainF
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H5 G21 R25 R44 E76 R88 S91 S204 D205 I207 R218
Catalytic site (residue number reindexed from 1) H4 G20 R24 R43 E75 R87 S90 S203 D204 I206 R217
Enzyme Commision number 2.4.2.1: purine-nucleoside phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DIH F H5 R44 H4 R43
BS02 DIH F M65 S91 C92 F160 V179 E180 M181 E182 D205 I207 M64 S90 C91 F159 V178 E179 M180 E181 D204 I206
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004731 purine-nucleoside phosphorylase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006152 purine nucleoside catabolic process
GO:0009116 nucleoside metabolic process
GO:0009164 nucleoside catabolic process
GO:0042278 purine nucleoside metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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External links
PDB RCSB:3occ, PDBe:3occ, PDBj:3occ
PDBsum3occ
PubMed
UniProtB1JL34|DEOD_YERPY Purine nucleoside phosphorylase DeoD-type (Gene Name=deoD)

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