Structure of PDB 3o8o Chain F

Receptor sequence
>3o8oF (length=762) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
QKAIAVMTSGGDAPGMNSNVRAIVRSAIFKGCRAFVVMEGYEGLVRGGPE
YIKEFHWEDVRGWSAEGGTNIGTARCMEFKKREGRLLGAQHLIEAGVDAL
IVCGGDGSLTGADLFRSEWPSLIEELLKTNRISNEQYERMKHLNICGTVG
SIDNDMSTTDATIGAYSALDRICKAIDYVEATANSHSRAFVVEVMGRNCG
WLALLAGIATSADYIFIPEKPATSSEWQDQMCDIVSKHRSRGKRTTIVVV
AEGAIAADLTPISPSDVHKVLVDRLGLDTRITTLGHVQRGGTAVAYDRIL
ATLQGLEAVNAVLESTPDTPSPLIAVNENKIVRKPLMESVKLTKAVAEAI
QAKDFKRAMSLRDTEFIEHLNNFMAINSADHNEPKLPKDKRLKIAIVNVG
APAGGINSAVYSMATYCMSQGHRPYAIYNGWSGLARHESVRSLNWKDMLG
WQSRGGSEIGTNRVTPEEADLGMIAYYFQKYEFDGLIIVGGFEAFESLHQ
LERARESYPAFRIPMVLIPATLSNNVPGTEYSLGSDTALNALMEYCDVVK
QSASSTRGRAFVVDCQGGNSGYLATYASLAVGAQVSYVPEEGISLEQLSE
DIEYLAQSFEKAEGRGRFGKLILKSTNASKALSATKLAEVITAEADGRFD
AKPAYPGHVQQGGLPSPIDRTRATRMAIKAVGFIKDNQAAIAEARAAEEN
FNADDKTISDTAAVVGVKGSHVVYNSIRQLYDYETEVSMRMPKVIHWQAT
RLIADHLVGRKR
3D structure
PDB3o8o The Crystal Structures of Eukaryotic Phosphofructokinases from Baker's Yeast and Rabbit Skeletal Muscle.
ChainF
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G206 R270 C271 D301 G345 S346 D348 D350 R392
Catalytic site (residue number reindexed from 1) G11 R75 C76 D106 G150 S151 D153 D155 R197
Enzyme Commision number 2.7.1.11: 6-phosphofructokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F6P F R383 R475 R188 R280
BS02 F6P F D348 M390 R392 E447 H481 R484 D153 M195 R197 E252 H286 R289
BS03 FDP F R658 S718 Q761 H853 R935 R463 S523 Q566 H658 R740
Gene Ontology
Molecular Function
GO:0003872 6-phosphofructokinase activity
GO:0005524 ATP binding
Biological Process
GO:0006002 fructose 6-phosphate metabolic process
GO:0006096 glycolytic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3o8o, PDBe:3o8o, PDBj:3o8o
PDBsum3o8o
PubMed21241708
UniProtP16862|PFKA2_YEAST ATP-dependent 6-phosphofructokinase subunit beta (Gene Name=PFK2)

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