Structure of PDB 3nc0 Chain F

Receptor sequence
>3nc0F (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRG
PIKFNVWDTAGLEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRD
LVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNF
EKPFLWLARKLIGDPNLEFVAMP
3D structure
PDB3nc0 NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
ChainF
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP F G20 T21 G22 K23 T24 T25 E36 K37 K38 Y39 A41 T42 G68 N122 K123 D125 I126 S150 A151 K152 G13 T14 G15 K16 T17 T18 E29 K30 K31 Y32 A34 T35 G61 N115 K116 D118 I119 S143 A144 K145
BS02 MG F T24 T42 D65 T17 T35 D58
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006913 nucleocytoplasmic transport

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Molecular Function
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Biological Process
External links
PDB RCSB:3nc0, PDBe:3nc0, PDBj:3nc0
PDBsum3nc0
PubMed20972448
UniProtP62826|RAN_HUMAN GTP-binding nuclear protein Ran (Gene Name=RAN)

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