Structure of PDB 3nby Chain F

Receptor sequence
>3nbyF (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]
VQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP
IKFNVWDTAGLEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL
VRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFE
KPFLWLARKLIGDPNLEFVAM
3D structure
PDB3nby NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
ChainF
Resolution3.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG F T24 T42 T16 T34
BS02 GTP F G20 G22 K23 T24 T25 F35 E36 K37 Y39 A41 T42 A67 N122 K123 D125 I126 S150 A151 K152 G12 G14 K15 T16 T17 F27 E28 K29 Y31 A33 T34 A59 N114 K115 D117 I118 S142 A143 K144
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006913 nucleocytoplasmic transport

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Molecular Function
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Biological Process
External links
PDB RCSB:3nby, PDBe:3nby, PDBj:3nby
PDBsum3nby
PubMed20972448
UniProtP62826|RAN_HUMAN GTP-binding nuclear protein Ran (Gene Name=RAN)

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