Structure of PDB 3mq6 Chain F

Receptor sequence
>3mq6F (length=338) Species: 1911 (Streptomyces griseus) [Search protein sequence]
PFTYSIEATRNLATTERCIQDIRNAPVRNRSTQFQLAQQNMLAYTFGEVI
PGFASAGINGMDYRDVIGRPVENAVTEGTHFFRDDFRVDSNAKAKVAGDI
FEIVSSAVMWNCAARWNSLMVGEGWRSQPRYSRPTLSPSPRRQVAVLNLP
RSFDWVSLLVPESQEVIEEFRAGLRKDGLGLPTSTPDLAVVVLPEEFQND
EMWREEIAGLTRPNQILLSGAYQRLQGRVQPGEISLAVAFKRSLRSDRLY
QPLYEANVMQLLLEGKLGAPKVEFEVHTLAPEGTNAFVTYEAASLYGLAE
GRSAVHRAIRELYVPPTAADLARRFFAFLNERMELVNG
3D structure
PDB3mq6 Domain swapping in allosteric modulation of DNA specificity.
ChainF
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F A95 K96 G99 R152 S153 K242 R243 S244 R246 R249 A94 K95 G98 R151 S152 K241 R242 S243 R245 R248 PDBbind-CN: Kd=0.6nM
BS02 dna F R31 T33 Q36 L37 Q39 Q40 D90 N92 A93 K96 R246 S247 D248 R30 T32 Q35 L36 Q38 Q39 D89 N91 A92 K95 R245 S246 D247 PDBbind-CN: Kd=0.6nM
BS03 CA F D188 F241 D187 F240
BS04 CA F E103 N149 L150 E102 N148 L149
Gene Ontology
Molecular Function
GO:0042802 identical protein binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3mq6, PDBe:3mq6, PDBj:3mq6
PDBsum3mq6
PubMed21151881
UniProtQ9F6L0

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