Structure of PDB 3mn6 Chain F

Receptor sequence
>3mn6F (length=360) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
VAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRDSYVGDEAQSKRGIL
TLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKAN
REKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPI
YEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTEEREIVRDIKEK
LCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNERFRCPEALFQPS
FLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQK
EITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDES
GPSIVHRKCF
3D structure
PDB3mn6 Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation.
ChainF
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F G23 D24 D25 G19 D20 D21
BS02 ATP F G13 S14 G15 K18 G156 D157 G158 V159 K213 E214 G302 M305 Y306 K336 G9 S10 G11 K14 G141 D142 G143 V144 K198 E199 G287 M290 Y291 K321
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000281 mitotic cytokinesis
GO:0006338 chromatin remodeling
GO:0007291 sperm individualization
GO:0030723 ovarian fusome organization
GO:0032507 maintenance of protein location in cell
GO:0035148 tube formation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0031011 Ino80 complex
GO:0035060 brahma complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3mn6, PDBe:3mn6, PDBj:3mn6
PDBsum3mn6
PubMed20538977
UniProtP10987|ACT1_DROME Actin-5C (Gene Name=Act5C)

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