Structure of PDB 3jbq Chain F

Receptor sequence
>3jbqF (length=328) Species: 9913 (Bos taurus) [Search protein sequence]
SHMEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTD
LNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKA
GKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIM
EHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKR
RGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAEL
VATEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVCTQLYEA
LTHVSEDCFPLLDGCRKNRQKWQALAEQ
3D structure
PDB3jbq Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6.
ChainF
Resolution11.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F N661 S663 Q666 H678 S679 L725 A726 I729 K730 I802 M804 L816 G819 F820 F823 N130 S132 Q135 H147 S148 L194 A195 I198 K199 I271 M273 L285 G288 F289 F292
Gene Ontology
Molecular Function
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0008081 phosphoric diester hydrolase activity
Biological Process
GO:0007165 signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:3jbq, PDBe:3jbq, PDBj:3jbq
PDBsum3jbq
PubMed25809480
UniProtP16586;
Q28156

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