Structure of PDB 3iyd Chain F

Receptor sequence
>3iydF (length=479) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MEGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYNRVEAEEARLSDLI
TGFVDPNAEEDLAPTATHVGSELSQEDLDIDPELAREKFAELRAQYVVTR
DTIKAKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRT
QERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHD
VSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEA
NLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYAT
WWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEE
LAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPL
DSATTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDHTLEEVGKQFDV
TRERIRQIEAKALRKLRHPSRSEVLRSFL
3D structure
PDB3iyd Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
ChainF
Resolution19.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F W433 V454 H455 D581 V582 E585 R586 Q589 W301 V322 H323 D449 V450 E453 R454 Q457
BS02 dna F R397 I457 N461 D570 T572 R588 R265 I325 N329 D438 T440 R456
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0016987 sigma factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0009408 response to heat
GO:0010468 regulation of gene expression
GO:0045892 negative regulation of DNA-templated transcription
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0000345 cytosolic DNA-directed RNA polymerase complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1903865 sigma factor antagonist complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3iyd, PDBe:3iyd, PDBj:3iyd
PDBsum3iyd
PubMed19903881
UniProtP00579|RPOD_ECOLI RNA polymerase sigma factor RpoD (Gene Name=rpoD)

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