Structure of PDB 3fmt Chain F

Receptor sequence
>3fmtF (length=157) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MKTIEVDDELYSYIASHTKHIGESRSDILRRMLKFKPVKTIKDKVRAMRE
LLLSDEYAEQKRAVNRFMLLLSTLYSLDAQAFAEATESLHGRTRVYFAAD
EQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMIEHIMQSMQFPAELI
EKVCGTI
3D structure
PDB3fmt Structural insights into the cooperative binding of SeqA to a tandem GATC repeat
ChainF
Resolution2.983 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F R86 A87 V88 R116 E125 K136 K138 T151 N152 T153 R62 A63 V64 R92 E101 K112 K114 T127 N128 T129
BS02 dna F G115 R116 R118 Y120 Q134 N150 R155 G91 R92 R94 Y96 Q110 N126 R131
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0010385 double-stranded methylated DNA binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
GO:0044729 hemi-methylated DNA-binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0007062 sister chromatid cohesion
GO:0008156 negative regulation of DNA replication
GO:0009314 response to radiation
GO:0032297 negative regulation of DNA-templated DNA replication initiation
GO:0090143 nucleoid organization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0032991 protein-containing complex
GO:1990097 SeqA-DNA complex

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Cellular Component
External links
PDB RCSB:3fmt, PDBe:3fmt, PDBj:3fmt
PDBsum3fmt
PubMed19304745
UniProtP0AFY8|SEQA_ECOLI Negative modulator of initiation of replication (Gene Name=seqA)

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