Structure of PDB 2z4e Chain F

Receptor sequence
>2z4eF (length=285) Species: 9606 (Homo sapiens) [Search protein sequence]
YLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIAN
KGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNW
IQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTS
TADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHN
GMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKAS
TPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
3D structure
PDB2z4e Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
ChainF
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F F295 D297 T305 F322 Q329 D330 K338 C339 H340 Y363 D364 F187 D189 T197 F214 Q221 D222 K230 C231 H232 Y255 D256
BS02 CA F D318 D320 F322 G324 D210 D212 F214 G216
BS03 CA F D294 G296 D298 P299 D301 D186 G188 D190 P191 D193
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2z4e, PDBe:2z4e, PDBj:2z4e
PDBsum2z4e
PubMed17688324
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

[Back to BioLiP]