Structure of PDB 2wzy Chain F

Receptor sequence
>2wzyF (length=208) Species: 6500 (Aplysia californica) [Search protein sequence]
LHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNE
VDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPV
QVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVY
SGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVN
LVVKFRER
3D structure
PDB2wzy Structural Determinants in Phycotoxins and Achbp Conferring High Affinity Binding and Nicotinic Achr Antagonism.
ChainF
Resolution2.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SQX F Y93 K143 W147 V148 Y188 Y195 Y94 K144 W148 V149 Y189 Y196 PDBbind-CN: -logKd/Ki=10.72,Kd=19pM
BS02 SQX F Y55 I118 S167 Y56 I119 S168 PDBbind-CN: -logKd/Ki=10.72,Kd=19pM
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:2wzy, PDBe:2wzy, PDBj:2wzy
PDBsum2wzy
PubMed20224036
UniProtQ8WSF8

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