Structure of PDB 2o7u Chain F

Receptor sequence
>2o7uF (length=329) Species: 9606 (Homo sapiens) [Search protein sequence]
DKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI
AANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVK
KDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVAN
FFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDV
AFVEHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVV
ARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFEDSAHGF
LKVPPRMDAKMYLGYEYVTAIRNLREGTC
3D structure
PDB2o7u Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.
ChainF
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE F D63 Y95 Y188 H249 D61 Y93 Y186 H247
BS02 CO3 F D63 Y95 T120 R124 A126 G127 Y188 D61 Y93 T118 R122 A124 G125 Y186
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:2o7u, PDBe:2o7u, PDBj:2o7u
PDBsum2o7u
PubMed17327678
UniProtP02787|TRFE_HUMAN Serotransferrin (Gene Name=TF)

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