Structure of PDB 2j0y Chain F

Receptor sequence
>2j0yF (length=215) Species: 9606 (Homo sapiens) [Search protein sequence]
LTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRR
VDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRTDLVDF
EDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQ
DNDLNTGNCAVMFQGAWWYKNCHTSNLNGRYLRGTHGSFANGINWKSGKG
YNYSYKVSEMKVRPA
3D structure
PDB2j0y Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins.
ChainF
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BGC F W134 E190 Q223 W61 E117 Q150
BS02 BGC F D133 A135 D60 A62
BS03 BGC F D129 Y131 R132 D133 K221 D56 Y58 R59 D60 K148
BS04 CA F D224 D226 N228 G230 D151 D153 N155 G157
External links
PDB RCSB:2j0y, PDBe:2j0y, PDBj:2j0y
PDBsum2j0y
PubMed17215869
UniProtQ15485|FCN2_HUMAN Ficolin-2 (Gene Name=FCN2)

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