Structure of PDB 2hrd Chain F

Receptor sequence
>2hrdF (length=245) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2) [Search protein sequence]
SKSDVFHLGLTKNDLQGAQLAIVPGDPERVEKIAALMDKPVKLASHREFT
SWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPH
INVGDVLVTTASVRLDGASLHFAPMEFPAVADFACTTALVEAAKSIGATT
HVGVTASSDTFYPGQERYDTYSGRVVRRFKGSMEEWQAMGVMNYEMESAT
LLTMCASQGLRAGMVAGVIVNRTQQEIPNESHAVKIVVEAARRLL
3D structure
PDB2hrd Crystal structure of the uridine phosphorylase from Salmonella typhimurium in complex with thymine and phosphate ion at 1.70A resolution
ChainF
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H4008 G4026 R4030 R4048 E4080 R4091 T4094 R4168 I4220 V4221 R4223
Catalytic site (residue number reindexed from 1) H7 G25 R29 R47 E79 R90 T93 R167 I219 V220 R222
Enzyme Commision number 2.4.2.3: uridine phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TDR F T4094 F4162 Q4166 R4168 E4196 M4197 I4220 T93 F161 Q165 R167 E195 M196 I219
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004850 uridine phosphorylase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0047847 deoxyuridine phosphorylase activity
Biological Process
GO:0009116 nucleoside metabolic process
GO:0009164 nucleoside catabolic process
GO:0009166 nucleotide catabolic process
GO:0044206 UMP salvage
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:2hrd, PDBe:2hrd, PDBj:2hrd
PDBsum2hrd
PubMed
UniProtP0A1F6|UDP_SALTY Uridine phosphorylase (Gene Name=udp)

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