Structure of PDB 2gwc Chain F

Receptor sequence
>2gwcF (length=439) Species: 3707 (Brassica juncea) [Search protein sequence]
VATEPLTREDLIAYLASGCKSKEKWRIGTEHEKFGFEVNTLRPMKYDQIA
ELLNSIAERFEWEKVMEGDKIIGLKQGKQSISLEPGGQFELSGAPLETLH
QTCAEVNSHLYQVKAVAEEMGIGFLGMGFQPKWRREDIPTMPKGRYDIMR
NYMPKVGSLGLDMMLRTCTVQVNLDFSSEADMIRKFRAGLALQPIATALF
ANSPFTEGKPNGFLSMRSHIWTDTDKDRTGMLPFVFDDSFGFEQYVDYAL
DVPMYFAYRNGKYVDCTGMTFRQFLAGKLPCLPGELPTYNDWENHLTTIF
PEVRLKRYMEMRGADGGPWRRLCALPAFWVGLLYDEDVLQSVLDLTADWT
PAEREMLRNKVPVTGLKTPFRDGLLKHVAEDVLKLAKDGLERRGYKEVGF
LNAVTEVVRTGVTPAENLLEMYNGEWGQSVDPVFQELLY
3D structure
PDB2gwc Structural basis for the redox control of plant glutamate cysteine ligase.
ChainF
Resolution2.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.2: glutamate--cysteine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG F E107 E159 E165 E32 E84 E90
BS02 BSC F E107 E159 P160 T242 C243 T244 R292 F375 R387 E32 E84 P85 T167 C168 T169 R217 F300 R312
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004357 glutamate-cysteine ligase activity
Biological Process
GO:0006750 glutathione biosynthetic process
GO:0042398 cellular modified amino acid biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2gwc, PDBe:2gwc, PDBj:2gwc
PDBsum2gwc
PubMed16766527
UniProtO23736|GSH1_BRAJU Glutamate--cysteine ligase, chloroplastic (Gene Name=GSH1)

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