Structure of PDB 2c38 Chain F

Receptor sequence
>2c38F (length=241) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
ERPKLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAA
VYGPKEMHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVI
REALESAVLVELFPRTAIDVFTEILQADAGSRLVSLMAASLALADAGIPM
RDLIAGVAVGKADGVIILDLNETEDMWGEADMPIAMMPSLNQVTLFQLNG
SMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEFKEEGV
3D structure
PDB2c38 Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
ChainF
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP F T88 R99 A136 S138 R139 E179 D182 T81 R92 A129 S131 R132 E172 D175
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003723 RNA binding
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters
Biological Process
GO:0006401 RNA catabolic process
GO:0016075 rRNA catabolic process
Cellular Component
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:2c38, PDBe:2c38, PDBj:2c38
PDBsum2c38
PubMed16285928
UniProtQ9UXC2|RRP41_SACS2 Exosome complex component Rrp41 (Gene Name=rrp41)

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