Structure of PDB 2ae8 Chain F

Receptor sequence
>2ae8F (length=170) Species: 158879 (Staphylococcus aureus subsp. aureus N315) [Search protein sequence]
MIYQKQRTQLNISISDDQSPSHINTGVGFLNHMLTLFTFHSGLSLNIEAQ
GDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLARVVVDISG
RPYLSFNASLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHH
EIEAIFKAFSRALGIALTAT
3D structure
PDB2ae8 Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315
ChainF
Resolution2.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.19: imidazoleglycerol-phosphate dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG F H62 E66 H53 E57
BS02 MG F H36 H158 E162 H32 H149 E153
Gene Ontology
Molecular Function
GO:0004424 imidazoleglycerol-phosphate dehydratase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ae8, PDBe:2ae8, PDBj:2ae8
PDBsum2ae8
PubMed
UniProtP64373|HIS7_STAAN Imidazoleglycerol-phosphate dehydratase (Gene Name=hisB)

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